A: Maybe that has something to do with it.
B: If that’s it. I find it very depressing.
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A: Does this have anything to do with you?
B: Yes, it does.
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A: How are you related to him?
B: He’s my uncle.
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A: Are these two related to each other?
B: No, there’s no relation.
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A: Are you involved in this?
B: No, I’m not.
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A: How is this connected with that?
B: There’s no connection.
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A: Is there any relationship between weight and health?
B: Yes, there is.
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A: Does your work have anything common with his work?
B: No, nothing in common.